A Pharmaceutical Emulsion Mixer Machine is a vacuum emulsifying mixer machine that typically consists of a primary homogenizing mixer, an oil phase mixer, a water phase mixer, a vacuum system, a hydraulic lifting system, a materials circulation system, a heating and cooling system, a temperature control system, and an electrical control panel, among other components.
The primary homogenizing mixer consists of a wall scraper, two-holed, fixed propellers, and a vertical-type inline high-shear mixer installed at the vessel’s base. The bottom homogenizer has a rotor with three layers of teeth and a stator with two. The rotor’s tangent is the path of an external circulation pipe that joins the tank’s top rim.
Both the oil and water component mixers are built in the same manner. A high-speed disperser, attached to the top of the lid, aids in the dissolution of the components. Some will maintain only the primary homogenizer and leave the oil and water phase mixers.
How Does an Emulsion Mixer Machine work?
The exterior anchor agitator spins continuously clockwise throughout the mixing process. The materials are scraped off the wall of the mixing tank and moved upward with the help of the connected Teflon blades so that they don’t get burned and don’t constantly adhere to the wall.
The cream is pushed downhill into the high-speed homogenizing and emulsifying phase by the two fixed impellers, which remain stationary and provide a counterforce to the materials. The perforations in the paddles allow the cream to flow through, resulting in a more thorough blending.
The cream continuously circles the container with the opposing forces of the impellers and the scraper. As the cream combines well, the heat from the jacket immediately spreads through the inside wall to every component.
The emulsion mixer machine’s rotor-stator homogenizer, also known as the emulsifier, consists of a rotor with three layers of teeth and a stator with two. Flanges link the rotor directly to the homogenizing motor. The rotor spins at high speed, creating a powerful suction force, by an ABB or Siemens motor spinning at 3000 rpm.
Using the top mouth of the homogenizer, materials are fed into the rotor, where they are subsequently sheared, emulsified, and homogenized by the rotor and stator. The particles are then propelled through the pipeline along the rotor’s tangent at high speeds. The cream returns to the mixing tank for further emulsification and homogenization through the external circulation line.
Both of the above modes of force, slow and high, are continuous. The cream thoroughly blends, distributes, emulsifies, and homogenizes by the pipeline’s revolving action.
Easily extract bubbles during mixing, dispersing, and homogenizing using a water ring-style vacuum pump (-0.09Mpa). As a bonus, it facilitates the components’ transit from the oil and water phase mixers to the primary homogenizer. Even miniature fragrances are vacuum-sucked to keep the dust-out.
The cover of the main homogenizing mixer lifts with the help of a hydraulic oil pump. It has safety features to ensure that the mixing part won’t start when the cover lifts.
What are the features that make up a Pharmaceutical Emulsion Mixer Machine?
The following characteristics are advantageous in the pharmaceutical manufacturing process;
- Fully integrated mixing, agitating, dispersing, emulsifying, homogenizing, vacuum, and temperature control system
- Capacity ranges from 5L to 10000L.
- Ideal for cream and emulsion with viscosities ranging from 10,000 to 100,000 cps.
- Faster batch processing.
- Particles are uniform in size (less than 2 micrometers) and distribution.
- Pipe-connected vertical inline homogenizer for external emulsification and homogenization.
- Internal homogenizer mechanical seal cooling system extends homogenizing times.
- The homogenizer also functions as a transfer pump, allowing complete product discharge.
- Hole-studded, wall-scraping, fixed impellers provide a contra-mixing system.
- The pipe shape of the outer anchor agitator improves mixing and adds visual appeal.
- Homogenizer and agitator speeds are configurable.
- System for lifting using oil hydraulics that is simple to clean and maintain.
- Jackets with two layers for cooling and heating.
- A variety of steam and electric jacket styles are available.
- The primary vacuum homogenizer has dual temperature sensors and controls for its electrical heating.
- Eliminate entrapped air during the mixing and transporting processes using a vacuum system.
- Using pressurized air to assist in the release of the final cream.
- Vacuum and hydraulic pump safeguards, together with worker protection mechanisms, are many.
- Mirror-polished SS316L for all moving components.
- The spray ball has a connection to the user’s CIP system.
- The vacuum homogenizers feature requirements that are in line with cGMP standards.
- Simple button interface for quick adjustments.
What are the wide applications of a Pharmaceutical Emulsion Mixer Machine?
- Pharmaceuticals include ointments, dental composites, syrups, and injections.
- Food applications include mayonnaise, dressing, jam, butter, margarine, wasabi, etc.
- Toiletries and cosmetics, including cream, lotion, wax, mascara, gel, toothpaste, etc.
- Chemical products such as polyester, synthetic fiber, shoe cream, etc.
What are the Options of a Pharmaceutical Emulsion Mixer Machine for making Toothpaste, Creams, etc.?
- Cover welded or bolted down for cost savings.
- Several designs of slow-mixing components.
- Pre-mixer agitator frame for oil that moves slowly.
- The vertical inline homogenizer has additional inlet ports for incorporating both hot and cold liquids and powders.
- Achieve automation processes, including mixing, dispersing, emulsifying, homogenizing, vacuum, transferring, heating, chilling, etc., using a Delta, Schneider, or Siemens PLC.
- Weighing scales.
- Automation of liquid flow meters for oil and water supply
- Steam pressure considerations in pressure vessel design.
- SIP is accessible upon demand.
- Acceptable range of power sources.